Effect of esophageal cooling on ablation lesion formation in the left atrium: Insights from Ablation Index data in the IMPACT trial and clinical outcomes.

3.5 Impedance drop AI was found to have a highly significant but weak correlation with impedance drop that was similar in the protected group and the control group ( ρ = 0.16 – 0.25, p < 0.0001; Figure 4 ). 3.6 Lesion‐to‐lesion progression There was a closer spatial relationship between consecutive lesions (not necessarily adjacent lesions) in the protected group in the posterior part of the PV encircling lesion set but with no statistically significant difference (5.4 [IQR = 3.6 – 9] mm vs. 5.5 [IQR = 3.7 – 9.3] mm, p = 0.051).

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