Barely Significant
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Sacubitril/valsartan and loop diuretic requirement in heart failure with preserved ejection fraction in the PARAGON-HF trial.

Eur J Heart Fail · 2023 · PMC10092840 · PMID 36181769

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borderline significantno p-value reported
On the other hand, sacubitril/valsartan resulted in a borderline significant 17% reduction in new loop diuretic initiations and a small early net reduction in overall loop diuretic requirement.

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