Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson's Disease.

Specifically, a mild trend of activity at 3 mg/kg, was followed by 2.2- and 2.5-fold increases (both p < 0.05) in punished licks at 10 and 30 mg/kg, respectively ( Figure 3 ).

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