Cytokine concentration in peripheral blood of patients with colorectal cancer.

Front Immunol · 2023 · PMC10098211 · PMID 37063892

Europe PMC DOI

hedged sentence

0.0176

closest p · 0.4× alpha

0.0176

boldest claim

The sentences

an increasing trendp = 0.0176actually significant

In addition, the concentrations of IFN-γ, GM-CSF, and TNF-α in the peripheral blood of patients with stage IV colorectal cancer showed an increasing trend (one-way ANOVA, GM-CSF control vs stage IV, p = 0.0176; TNF-α stage II vs stage IV, p = 0.0378), suggesting a possible restoration of M1 macrophage-mediated anti-tumor function in colorectal cancer patients with distant metastases.

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