Global Increase of Antibiotic Resistance Genes in Conjugative Plasmids.

Microbiol Spectr · 2023 · PMC10100709 · PMID 36946731

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an increasing trendno p-value reported

KEYWORDS conjugative plasmid antibiotic resistance genes global increase antibiotics transmission The increasing plasmid-borne ARG abundance is significantly correlated with an increasing trend of antibiotic consumption, particularly in low-to-middle income countries.

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highly significantno p-value reported

Therefore, our analysis infers a highly significant global increase in the abundance of conjugative plasmids that harbor ARGs, which is correlated with a global increase in antibiotic consumption.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.