Identification of RNA Virus-Derived RdRp Sequences in Publicly Available Transcriptomic Data Sets.

Downstream of ORF3, the 3′ region contains several disjoint ORFs, three of which have highly significant a.a. matches to the Mononegavirales L protein (TBLASTN against KX884441.1 , E = 5 × 10 −13 for the shortest fragment) and together cover its RdRp, capping, connector, and methyltransferase domains (HHpred of concatenated a.a. sequences has an E = 5.1 × 10 −189 hit to PDB_mmCIF70_14Oct:6V85_A; fig. 8 A ).

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