Evaluation of preclinical efficacy of human umbilical cord mesenchymal stem cells in ankylosing spondylitis.

Front Immunol · 2023 · PMC10101200 · PMID 37063838

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a decreasing trendno p-value reported

Compared with the PBMC group stimulated by adding PHA, the secretion levels of TNF-α in the culture medium was significantly reduced under the co-culture condition of adding hUCMSCs ( Figures 4G–I ), and IL-17A also almost has a decreasing trend ( Figures 4J–L ).

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an increasing trendno p-value reported

Effects of hUCMSCs on thymus and spleen coefficients in PGISp mice Compared with normal mice, the spleen and thymus weight (p<0.01) of PGISp mice showed an increasing trend.

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