a decreasing trendp = 0.052
showed [ 64 ] that after 3 months of treatment with megestrol (a synthetic progestin that has been shown to increase appetite in patients [ 65 ]), the weight and BMI of dialysis patients increased significantly compared to the previous period and the changes were statistically significant ( p < 0.05); a decreasing trend towards total cholesterol concentration in the first 2 months of treatment ( p = 0.052) was also seen.