Barely Significant
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Ultrahigh-precision noble gas isotope analyses reveal pervasive subsurface fractionation in hydrothermal systems.

Sci Adv · 2023 · PMC10104464 · PMID 37058557

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may be significantno p-value reported
While this isotopic effect appears small (but nonnegligible) for He, being comparable to the actual precision of typical mass spectrometers, the magnitude of Ne isotopic anomalies generated by DTF may be significant, representing up to ~11% of Ne isotope signals expected for a pure upper mantle source ( 20 Ne/ 22 Ne ~ 12.5).

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