The present study was highly significant because it (1) identified the glucocorticoid receptor as a new regulator for control of prolonged surgical pain conditions; (2) suggested that short-term stress-mediated pain abnormality could be ameliorated by inhibition of glucocorticoid receptor and activation of downstream neuroprotective pathway; and (3) provided evidence that the prevention of perioperative stress may facilitate recovery of postoperative pain.
← all excerpts
Stress Induces Prolonged Pain Recovery After Surgery: Involvement of Glucocorticoid-Related Pathway.
1
—
—