Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs.

Front Cell Dev Biol · 2023 · PMC10113925 · PMID 37091981

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highly significantno p-value reported

We expand our knowledge about the distinct role of GFI1 in various cellular populations by showing that reduced levels of GFI1 and loss of Gfi1 lead to the significant expansion of LSK cells, but to a highly significant reduction of HSCs.

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