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Associations of advanced age with comorbidity, stage and primary subsite as contributors to mortality from colorectal cancer.

Front Public Health · 2023 · PMC10116414 · PMID 37089488

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an increasing trendno p-value reported
Some studies have reported that unlike colon cancer, rectal cancer mortality has an increasing trend in some countries including Australia, Canada and the United States and needs to be further investigated ( 35 , 36 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.