Tannic acid, an IL-1β-direct binding compound, ameliorates IL-1β-induced inflammation and cartilage degradation by hindering IL-1β-IL-1R1 interaction.

PLoS One · 2023 · PMC10118179 · PMID 37079558

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a decreasing trendno p-value reported

In contrast, the expression levels of IL-1β and IL-6 were significantly decreased by TA, while the expression level of MCP-1 showed a decreasing trend in the TA-treated group.

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