A comparison of simplified protocols of personalized dosimetry in NEN patients treated by radioligand therapy (RLT) with [¹⁷⁷Lu]Lu-DOTATATE to favor its use in clinical practice.

TIAC changed during RLT, showing an increasing trend from cycle I to cycle IV in the kidney (mean difference = − 0.21 ± 0.39 h, p < 0.01) and a decreasing one in the liver (mean difference = 5.1 ± 14.16 h, p < 0.01) and in the WB (mean difference = 9.37 ± 15.19 h, p < 0.01), but remained constant in spleen (mean difference = − 0.18 ± 0.96 h, p = 0.12) and red marrow (mean difference = − 0.10 ± 0.05 h, p = 0.64).

also in 37,734 other papers