Contextual modifiers of healthspan, lifespan, and epigenome in mice under chronic social stress.

Proc Natl Acad Sci U S A · 2023 · PMC10120026 · PMID 37043532

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may be significantno p-value reported

Conclusion Our study identified genetic and social factors determining the degree of vulnerability to the negative effect of chronic stress on survival and additionally shows how agonistic behavior and social rank may be significant modifiers of healthspan, DNA methylation pattern, and lifespan.

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