Two-tailed p values < 0.05 (∗) and 0.01 (∗∗) or 0.001 (∗∗∗) were considered statistically significant and highly significant, respectively. “ns” indicates nonsignificant differences. 3 Results 3.1 Drug repurposing screen to identify active compounds that block EV-A71 To screen the potential compounds that inhibit EV-A71 proliferation, an HTS assay was conducted to preliminarily identify the compounds that were measured by CPE.
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Identification of a novel binding inhibitor that blocks the interaction between hSCARB2 and VP1 of enterovirus 71.
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