Barely Significant
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Evaluation of Apically Extruded Debris and Cleaning Efficiency of the Pediatric Rotary File System and the Manual Nickel-Titanium File System.

Cureus · 2023 · PMC10122609 · PMID 37155435

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highly significantno p-value reported
[ 12 ] who found no considerable differences in the amount of smear layer for manual K-file and rotary ProFile at the cervical and middle thirds of the canals, but in the apical third, there was a highly significant difference, when they evaluated the cleaning efficacy of manual K flex files and rotary ProFile systems utilizing 30 single-rooted mandibular first premolars.

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