Transcription factor binding site orientation and order are major drivers of gene regulatory activity.

Nat Commun · 2023 · PMC10122648 · PMID 37087538

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highly significantno p-value reported

There were 89 transcription factor pairs (representing ~29% of the interactions) that showed highly significant differences in expression depending on TFBS order (Fig. 3b-e ; t-test, Bonferroni corrected).

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