Exploring choices of early nutritional support for patients with sepsis based on changes in intestinal microecology.

RESULTS In comparison with before nutritional support, the three groups after nutritional support presented: (1) Differences in the gut bacteria (Enterococcus increased in the TEN group, Campylobacter decreased in the TPN group, and Dialister decreased in the SPN group; all P < 0.05); (2) different trends in SCFAs (the TEN group showed improvement except for Caproic acid, the TPN group showed improvement only for acetic and propionic acid, and the SPN group showed a decreasing trend); (3) significant improvement of the nutritional and immunological indicators in the TEN and SPN groups, while only immunoglobulin G improved in the TPN group (all P < 0.05); and (4) a significant correlation was found between the gut bacteria, SCFAs, and nutritional and immunological indicators (all P < 0.05).

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The changes in the SCFAs before and after nutrition in the TEN (Figure 3 ), TPN (Figure 4 ), and SPN (Figure 5 ) groups were compared and all SCFAs in the TEN group showed an increasing trend except for caproic acid.

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