Vitamin B₁₂ status in infancy and the effect of a vitamin B₁₂ injection in infants with subclinical vitamin B₁₂ deficiency: study protocol for a register-based randomised controlled trial.

In the Indian study, where growth and neurodevelopment were secondary outcomes, daily supplementation with 1.8 μg vitamin B 12 for 6 months resulted in small, borderline significant, beneficial effects on neurodevelopment and growth. 12 13 The study in Nepal enrolled 600 infants who were supplemented with 2 μg vitamin B 12 or a placebo daily for 1 year.

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