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Peripheral blood T-lymphocyte subsets are potential biomarkers of disease severity and clinical outcomes in patients with ulcerative colitis: a retrospective study.

BMC Gastroenterol · 2023 · PMC10134527 · PMID 37106335

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a decreasing trendno p-value reported
The study found that UC patients had a reduced CD4 + /CD8 + ratio than HC, which indicated the immune function disorder [ 32 ], and the ratio exhibited a decreasing trend as the disease severity progressed.

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