Barely Significant
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Apolipoprotein E (APOE) Haplotypes in Healthy Subjects from Worldwide Macroareas: A Population Genetics Perspective for Cardiovascular Disease, Neurodegeneration, and Dementia.

Curr Issues Mol Biol · 2023 · PMC10137191 · PMID 37185708

Europe PMCDOI
1
hedged sentence
0.0260
closest p · 0.5× alpha
0.0260
boldest claim

The sentences

marginally significantp -value = 0.026actually significant
When focusing on the distribution of APOE isoforms within macroareas and a Chi-square test is performed, only the populations in the AFR macroarea provide a marginally significant result, with the Luhya (LWK) people highlighted as the only contribution towards significance (df = 2, p -value = 0.026), since this group presents a lower number of individuals with the ε2 and ε3 isoforms than what is expected, and a higher number of individuals with the ε4 isoform of APOE ( Figure 1 and Supplementary Table S3 ). 3.4.

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