Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry.

Int J Mol Sci · 2023 · PMC10139035 · PMID 37108137

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Furthermore, it is highly significant that MMP carboranes 1 (B1) and 2 (B2) are highly efficacious as BNCT agents despite the fact that the measured boron concentrations determined by ICP-OES in SCC VII and U87 tumor cells treated with these compound are extremely low.

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