Among European countries where a long history of ART and high ART coverage, but at the same time, baseline genotyping is a part of routine clinical practice, the overall prevalence of transmitted DR in treatment-naïve patients ranged from 12.8% to 14.5% and presented a decreasing trend [ 39 , 49 ].
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HIV-1 Drug Resistance among Treatment-Naïve Patients in Russia: Analysis of the National Database, 2006-2022.
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The temporal trends of sub-subtype A6 have decreased, whereas CRF63_02A6, CRF02_AG and other genetic variants (CRF01_AE, A1, 19_cpx, 14_BG, CRF01_AE/B, CRF20_BG, 56_cpx, C, 11_cpx, CRF06_cpx, F1) have been on an increasing trend since 2012 ( Figure S1 ).