Values with P < 0.05 and P < 0.01 were considered significant, and those with P < 0.001 were extremely significant. 3 Results 3.1 TGM2 expression was significantly up-regulated in MDCK low tumor-forming cells In our previous work, we screened a low tumorigenic cell line (MDCK-C09) and a high tumorigenic cell line [ 22 ] (WT) through monoclonal experiments.
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TGM2 inhibits the proliferation, migration and tumorigenesis of MDCK cells.
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