Maternal Serum Vitamin B12 during Pregnancy and Offspring Autism Spectrum Disorder.

Nutrients · 2023 · PMC10146734 · PMID 37111227

Europe PMC DOI

hedged sentences

0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

close to significancep = 0.064so close (0.05 < p ≤ 0.1)

A significant association was observed between maternal vitamin B12 levels in the highest quintile (≥81th percentile) and offspring childhood autism (aOR 1.59, 95% CI 1.06–2.41, p = 0.026) and the association was close to significance in the lowest quintile (aOR 1.49, 95% CI 0.98–2.26, p = 0.064), relative to the third quintile ( Figure 1 ).

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a statistical trendno p-value reported

Furthermore, in the current study, low levels of maternal vitamin B12 (<20th percentile) during early pregnancy evidenced a statistical trend toward association with offspring childhood autism.

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