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The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner.

Nat Commun · 2023 · PMC10147666 · PMID 37117181

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The 100x difference in luciferase activity between the human and mouse cells did not quite reach statistical significance due to high variation among the replicates in that experiment (Fig. 1a ).

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