Efficacy and safety of Omega-3 polyunsaturated fatty acids in adjuvant treatments for colorectal cancer: A meta-analysis of randomized controlled trials.

After subgroup analyses on different routes of administration, there was a positive trend of TNF-α when O3FAs were used in TPN (MD = −1.26, 95% CI: −2.25 to −0.27, p = 0.01, I 2 = 4%, n = 183 participants, Supplementary Table S5 ).

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