Transcriptional re-programming of insulin B-chain epitope-specific T-follicular helper cells into anti-diabetogenic T-regulatory type-1 cells.

Front Immunol · 2023 · PMC10154693 · PMID 37153608

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hedged sentence

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closest p · 0.0× alpha

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highly significantP<10 -15actually significant

Scatter plots of the log2FC values for differentially expressed genes in the tetramer+ cells arising in response to each pMHCII-NP type confirmed highly significant correlations among the scRNAseq profiles of the different tetramer specificities (P<10 -15 ; >60% of all the genes in each comparison undergo similar levels of upregulation or downregulation as compared to Tconv cells) ( Figure 2C ).

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