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Immune response elicited in the tumor microenvironment upon rMV-SLAMblind cancer virotherapy.

Cancer Sci · 2023 · PMC10154881 · PMID 36715555

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a slight trendno p-value reported
In spleens, the proportion of OVA + CD8 + T cells showed a slight trend to increase in rMV‐SLAMblind‐treated mice (Figure S5A , C ), although the numbers of CD8 + T cells and OVA tetramer + CD8 + T cells were nearly identical (Figure S5B , D ).

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a decreasing trendno p-value reported
Interestingly, the proportion of OVA tetramer + CD8 + T cells showed a decreasing trend following rMV‐SLAMblind treatment (Figure 5E,G ), whereas the accumulation of CD8 + T cells and OVA tetramer + CD8 + T cells in a couple of mice was observed in TILs in the rMV‐SLAMblind‐treated group (Figure 5F,H ).

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