Current Status of Low-Density Lipoprotein Cholesterol and Cardiovascular Diseases in Japan.

Noda et al 7) reported in a large cohort study involving 90000 residents of Ibaraki Prefecture an inverse association between LDL-cholesterol and intraparenchymal hemorrhage mortality, which revealed that LDL-cholesterol was likely a risk factor for hemorrhage instead of total cholesterol. Although stroke mortality has been declining since the 1960s, stroke still accounted for 16.6% of the common cause of needing nursing care, whereas there is an increasing trend of the incidence of CHD among men who live in the urban areas of Japan 8 , 9) .

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