Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression.

J Exp Clin Cancer Res · 2023 · PMC10165825 · PMID 37150829

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highly significantno p-value reported

Results from both Binding Analysis for Regulation of Transcription (BART) [ 70 ] and ChIP-X Enrichment Analysis 3 (ChEA3) [ 71 ] indicated TP63 as a highly significant TF regulating the genes in this histologic-grade associated gene module (ranked 1st by BART and 18th by ChEA3 MeanRank method; Supplementary Table S 6 ).

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