Barely Significant
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Genetic Polymorphisms in SLCO2B1 and ABCC1 Conjointly Modulate Atorvastatin Intracellular Accumulation in HEK293 Recombinant Cell Lines.

Ther Drug Monit · 2023 · PMC10168106 · PMID 36253893

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a nonsignificant trendP > 0.05actually significant
After 60 minutes of efflux time, a nonsignificant trend ( P > 0.05) of a higher efflux ratio for the double transfectant model HEK OATP2B1WT-MRP1var was observed compared with cell lines expressing WT MRP1 (HEK OATP2B1WT-MRP1WT and HEK OATP2B1var-MRP1WT ).

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