a nonsignificant trendP > 0.05
After 60 minutes of efflux time, a nonsignificant trend ( P > 0.05) of a higher efflux ratio for the double transfectant model HEK OATP2B1WT-MRP1var was observed compared with cell lines expressing WT MRP1 (HEK OATP2B1WT-MRP1WT and HEK OATP2B1var-MRP1WT ).