Since 2007, this disease has shown an increasing trend in major pig-farming countries, including the United States [ 3 ], Brazil [ 4 ], Colombia [ 5 ], Thailand [ 6 ], Vietnam [ 7 ], and China [ 8 ].
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Senecavirus A-induced glycolysis facilitates virus replication by promoting lactate production that attenuates the interaction between MAVS and RIG-I.
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