Diagnostic performance of different specimens in detecting enterovirus A71 in children with hand, foot and mouth disease.

Virol Sin · 2023 · PMC10176262 · PMID 36371008

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an increasing trendno p-value reported

After the sensitivity analysis, HFMD due to EV-A71 infection was redefined as an increasing trend in the EV-A71 NAb titre, a within 2-fold change from the acute to convalescent samples within three months, and a convalescent serum titre >512; HFMD caused by non-EV-A71 infection was defined as EV-A71 NAb titres <512 or a more than 2-fold decrease in the NAb titres of paired sera within 3 months.

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