Tumor Sink Effect with Prostate-Specific Membrane Antigen-Targeted Theranostics in Patients with Metastatic Castration-Resistant Prostate Cancer: Intra-Individual Evaluations.

Less closely aligned with observations of most [ 2 , 14 , 19 ], but not all [ 16 ], of the four previously published studies and of the single case report [ 20 ] examining the issue in patients with higher tumor burdens, our findings suggest only a possible trend towards a tumor sink effect of PSMA-targeted radiopharmaceuticals in the liver.

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