Genome-Wide Association Study Identifies Genetic Polymorphisms Associated with Estimated Minimum Effective Concentration of Fentanyl in Patients Undergoing Laparoscopic-Assisted Colectomy.

Although this SNP was also found to be nominally significantly associated with the estimated plasma and effect-site MECs in the present study in the additive model (combined β = −0.07784, nominal p = 0.00232, for the 0–6 h plasma MEC; combined β = −0.07517, nominal p = 0.00310, for the 0–12 h plasma MEC; combined β = −0.09432, nominal p = 0.00250, for the 0–

also in 672 other papers

The association between the SERP2 gene and the 0–6 h effect-site MEC was marginally significant (adjusted p = 0.05245; Supplementary Table S5 ).

also in 2,320 other papers

Among these, the rs966775 SNP that mapped to 5p13 had highly significant associations with 0–6 h plasma and 0–12 h effect-site MECs ( Table 1 and Table 2 ).

also in 11,749 other papers