Among these effects, the effects of aneuploidy on mitochondrial function and metabolic pathways of some amino acids were extraordinarily significant ( Figure 2 G,H), probably because the gene dosage imbalance in aneuploidy induces proteotoxic stress and activates autophagy to maintain proteostasis [ 52 ].
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Genome-Wide Expression Analysis of Long Noncoding RNAs and Their Target Genes in Metafemale <i>Drosophila</i>.
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