highly significantp < 0.0001
6.65 X 2 X 3 − 35.03 X 1 2 − 47.97 X 2 2 − 29.11 X 3 2 Y 2 (TFC) = 58.85 + 5.13 X 1 + 0.27 X 2 − 1.13 X 3 − 0.43 X 1 X 2 + 0.80 X 1 X 3 − 0.39 X 2 X 3 − 4.51 X 1 2 − 2.53 X 2 2 − 1.71 X 3 2 The results of the analysis of variance in Table 2 suggest that the fitted models for TPC and TFC were both highly significant ( p < 0.0001), while the lack of fit was not significant ( p -values: 0.2161 and 0.3343, respectively), indicating a good fitness for the models.