Barely Significant
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Optimization of a Mucoadhesive Vaginal Gel Containing Clotrimazole Using a D-Optimal Experimental Design and Multivariate Analysis.

Polymers (Basel) · 2023 · PMC10181139 · PMID 37177171

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closest p · 0.0× alpha
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The sentences

highly significantp < 0.001actually significant
Even though the difference between the mean inhibition zone diameter for the optimized CLT-MVG formulation and the mean inhibition zone diameter for the CLT solution was highly significant ( p < 0.001—Student’s paired t -test), a mean difference of only 5.55 mm is not relevant in practice, as long as all diameters are situated above 45 mm (min diameter = 47 mm, max diameter = 61 mm).

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