Generally, when keeping the other properties of NPs such as surface charge constant, their hydrophobicity has a positive trend with their cytotoxicity. 74 Muthukumarasamyvel et al. 81 controlled the hydrophobicity of dicationic amphiphile-stabilized AuNPs by conjugating the dicationic functionality with different numbers and locations of H and OH groups.
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The toxicity of nanoparticles and their interaction with cells: an <i>in vitro</i> metabolomic perspective.
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