The cuproptosis-associated 11 gene signature as a predictor for outcomes and response to Bacillus Calmette-Guerin and immune checkpoint inhibitor therapies in bladder carcinoma.

Univariable COX regression OS analyses of age, gender, stage, grade, and the CuAGS-11 model showed that age (>60 yrs), advanced stages and CuAGS-11 (high-risk) were associated with significantly shorter OS ( Figure 4B ), while all these three variables remained highly significant in the multivariable COX regression analysis ( Figure 4C ).

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