Establishment of a New Model of Lumbar Intervertebral Disc Degeneration With Pathological Characteristics.

However, the expression of MMP-3 and PLA2 in the unilateral and bilateral ischemic groups showed an increasing trend, with the highest levels observed in the bilateral ischemic group.

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With increasing postoperative time, the mRNA expression of collagen II and aggrecan in the different groups showed a decreasing trend to different degrees, but in the normal control group expression was significantly higher than the unilateral or bilateral ischemia groups ( Figure 3A-F ).

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