Injectable sustained-release poly(lactic-co-glycolic acid) (PLGA) microspheres of exenatide prepared by supercritical fluid extraction of emulsion process based on a design of experiment approach.

87 , 88 , 89 A p ‐value less than 0.05 and 0.01 indicates that the model terms are statistically significant at the 95% confidence level and are highly significant at the 99% confidence level. 90 , 91 , 92 Thus, p values <0.05 obtained from ANOVA were considered statistically significant.

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