A total of 30 significantly changed metabolites between the ISH group and SDH group samples were identified, as illuminated in the heat map, of which, 9 showed a reduced trend, and 21 displayed an increasing trend in SDH ( Supplementary Figures S2B,D ).
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A cross-sectional study identifying disparities in serum metabolic profiles among hypertensive patients with ISH, IDH and SDH subtypes.
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Moreover, in pulmonary arterial HTN animal models, another study indicated that stearoylcarnitine was slightly elevated compared with healthy controls, with marginally significant ( 44 ).