Barely Significant
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Impact of Introducing Infliximab Biosimilars on Total Infliximab Consumption and Originator Infliximab Prices in Eight Regions: An Interrupted Time-Series Analysis.

BioDrugs · 2023 · PMC10195719 · PMID 36952213

2
hedged sentences
0.0010
closest p · 0.0× alpha
0.0020
boldest claim

The sentences

an increasing trendP < 0.001actually significant
A stable trend was observed in Hong Kong ( P = 0.605) and the UK ( P = 0.155), while in the USA there was an increasing trend in price where the originator infliximab price increased at a rate of 5.14 USD/SU per quarter [( P < 0.001), Fig. 3 ; Table 2 ].

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a decreasing trendP = 0.002actually significant
Before biosimilars were introduced, originator infliximab prices presented a decreasing trend in Australia ( P = 0.002), Canada ( P < 0.001), India ( P < 0.001), Japan ( P < 0.001), and Korea ( P < 0.001).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.