Hypermethylation at CREBBP Is Associated with Cognitive Impairment in a Mexican American Cohort.

J Alzheimers Dis · 2023 · PMC10200223 · PMID 36872777

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highly significantno p-value reported

Both highly significant sites (cg13135255 and cg27002303) among MAs and NHWs respectively have been associated with either cognitive function or development, therefore environmental factors influencing methylation at these sites could possibly contribute to AD pathogenesis collectively alongside other AD risk associated CpG sites.

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