Fecal metabolomics combined with 16S rRNA gene sequencing to analyze the effect of Jiaotai pill intervention in type 2 diabetes mellitus rats.

Compared with the model group, the serum levels of FINS, TG, and LDL in the JTP group rats were highly significantly lower ( p < 0.01), the level of TC had a decreasing trend, the level of HbA1c was significantly lower ( p < 0.05), and the level of IL-10 was highly significant higher ( p < 0.01), the levels of HbA1c, FINS, TC, TG, and LDL in the MET group were highly significantly lower ( p < 0.01), and IL-10 levels were highly significantly increased ( p < 0.01) ( Figures 1C–H ). 3.3.

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Rat FBG results During the model establishment period, the fasting blood glucose (FBG) of rats showed an increasing trend in the high-fat diet stage.

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