In two large prospective cohorts, there was no consistent correlation between the blood group and the risk of CRC but regarding blood group B there was a borderline significant correlation with the overall risk of CRC without a clear explanation of the biological mechanism for the differential association of group B compared with group A antigen with cancer.
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Correlation between blood group, Rh, and obesity with colorectal carcinoma among patients attending Al-Kindy Teaching Hospital/Baghdad: a case-control study.
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P -value of 0.00001 which is highly significant.
The Peak incidence of patients with CRC occurred in patients with blood group A+ 42 cases ( 41.17%) followed by blood group O+ 38 cases ( 34.44%) which were marginally significant, with a P -value of 0.00049.