Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis.

However, the mutations caused a mild trend in the elongation profiles of sebaceous CEs that followed the Meibomian WE pattern: An increase in the apparent abundance of shorter chain CEs at the expense of the longer chain counterparts was observed, though the magnitude of this change was rather moderate.

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